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Under disorders of small CB1R density, THC antagonises endogenous agonists possessing increased receptor efficacy than THC19. THC also allosterically modulates opioid receptors20, which can give further oblique routes for altering dopamine transmission21. Furthermore, THC has psychoactive metabolites with CB1R affinity, more complicating the analys
Amongst The most crucial parts of the ECS would be the receptors. The CB1 and CB2 receptors are the main receptors in This technique and can be found throughout the human body. THC, a plant cannabinoid, is understood to connect with each of these receptors.In terms of the entourage effect, the most supported illustrations relate to THC and CBD. Can